Celecoxib-d7 is the deuterium-labeled form of Celecoxib, a selective non-steroidal anti-inflammatory drug (NSAID) and COX-2 inhibitor with an IC50 of 40 nM. This compound can serve as a tracer and internal standard for quantitative analysis methods like NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes into drug molecules, such as deuteration, is used for quantitation during drug development and can influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes for quantitation during drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs